Embark from Rome to Orvieto, famed for its stunning duomo atop limestone rock. Dive into Siena's charm, exploring Piazza del Campo and the majestic duomo. Discover Florence's Renaissance marvels, from guided tours to culinary delights. Visit Pienza's UNESCO heritage sites and indulge in Pecorino cheese. End with a winery tour and scenic stop at Bagno Vignoni.