Assisi, the birthplace of St. Francis, has many sites relating to the life of the Saint which can be visited. The city’s masterpiece, the Basilica of St. Francis is important both from a religious and artistic perspective. Move on to San Giovanni Rotondo, located in the south of Italy which is the second most visited Catholic Shrine in the world. Saint Padre Pio was a Capuchin Friar, priest and mystic known for his devotion to God, care for the sick and supernatural gifts. He died in 1968 and was declared a Saint in 2002. Bari, cultural crossroads since ancient times, is an ideal starting point, a city where two souls meet, the old town and the modern town. A wonderful example of Apulian Romanesque architecture is the imposing Basilica di San Nicola (Saint Nicholas's Basilica), where the holy relics of the famous saint are kept.